Opacification of intraocular lenses: laboratory and clinical findings

Abstract

Background: Since their introduction the spectrum of complications of intraocular lenses (IOLs) has changed. Clouding of the IOL material is increasingly described in the literature as a reason for explantation. Objective: This study aimed to give an overview of the various pathologies of IOL material. Material and methods: The currently relevant types of IOL material opacities are summarized as well as their effects on the optical quality. Results and conclusion: In current IOL models calcification can occur in lenses made of hydrophilic acrylate, while in IOLs made of hydrophobic acrylate “glistenings” can develop. These different material opacifications have varying impacts on optical quality parameters and in general lead to an increased intraocular light scattering. In the case of intolerable IOL material opacification, the only treatment option is its removal and the implantation of a new IOL.