Sickle cell disease (SCD) is the most prevalent genetic disease in the world. In Brazil it occurs in one in every 1200 births. This high prevalence makes SCD a very important public health problem in Brazil. Vaso-occlusion and hemolysis are the hallmarks of the disease. Vaso-occlusion results in painful episodes which are the main cause of hospitalization among adults with SCD. Some patients experience episodes as often as 6 times per year. Persistent, severe sickle cell pain is a poor prognostic sign and a predictor for early death. The management of vaso-occlusion episodes is discussed here, as well as the related complications.
CITATION STYLE
Lobo, C. L. D. C., Marra, V. N., & Silva, R. M. G. (2007). Crises dolorosas na doença falciforme. Revista Brasileira de Hematologia e Hemoterapia, 29(3), 247–258. https://doi.org/10.1590/s1516-84842007000300011
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