Here we introduce entropy-based measures derived from information theory for detecting and characterizing epistasis in genetic association studies. We provide a general overview of the methods and highlight some of the modifications that have greatly improved its power for genetic analysis. We end with a few published studies of complex human diseases that have used these measures.
CITATION STYLE
Moore, J. H., & Hu, T. (2015). Epistasis analysis using information theory. Methods in Molecular Biology, 1253, 257–268. https://doi.org/10.1007/978-1-4939-2155-3_13
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