Clavukerin C, A new trinor-guaiane sesquiterpene having a hydroperoxy function, from the okinawan soft coral: Clavularia koellikeri

Abstract

A new trinor-guaiane sesquiterpene named clavukerin C (2), having a hydroperoxy function, was isolated together with clavukerin A (1), clavukerin B (3), and bicyclogermacrene (4) from the Okinawan soft coral (stolonifer) Clavularia koellikeri. The absolute stereo-structure of clavukerin C (2) was elucidated. Clavukerin B (3) was found to be identical with or antipodal to trinoranastreptene, which was previously reported as a liverwort metabolite. © 1984, The Pharmaceutical Society of Japan. All rights reserved.