Abstract
Blood cell production is maintained throughout life by hematopoietic stem cells (HSC), which reside in specific areas of the bone marrow (BM) referred to as niches. These niches regulate the self-renewal, proliferation, and migration of HSC and also integrate signals from the periphery to respond to the hematopoietic demand. In the last decade, several putative cellular components of the HSC niche have been identified. Here, we briefly review current knowledge on different putative niche cells and their regulation.
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CITATION STYLE
Lucas, D., Pinho, S., & Frenette, P. S. (2013). MSC niche for hematopoiesis. In Mesenchymal Stromal Cells: Biology and Clinical Applications (pp. 91–106). Springer New York. https://doi.org/10.1007/978-1-4614-5711-4_6
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