Topical immune response modifiers: Adjuvants

Abstract

The topical immune response modifier imiquimod is a low molecular weight heterocycline imidazoquinoline amine. Imiquimod stimulates both the innate and the acquired arms of the immune system via induction of T-helper-1 cytokines Imiquimod is Food and Drug Administration approved for the treatment of anogenital warts, but is widely used to treat other warts and molluscum contagiosum. Nonantiviral uses of imiquimod include actinic keratoses and superficial basal cell carcinomas. © 2008 Springer London.