Anticancer activity of Morus nigra leaves extract

Abstract

Plants are screened for treatment of many ailments including cancer because they possess certain potential constituents which are effective for treatment. The aim of this study was to evaluate the anticancer activity of Morus nigra leaves against human cervical cancer cell line (HeLa). n-Hexane and aqueous methanolic extract of plant’s leaves were made by maceration. Anticancer activity was estimated by methyl-thiazolyl-tetrazolium (MTT) assay and percentage inhibition of cells was calculated. Results of MTT showed that 100 μg/ml aqueous methanol extract of M. nigra inhibited 89.5-31.99% of HeLa cell line. It was concluded that M. nigra possess anticancer activity.