Studies on Agalwood (Jinko): X: Structures of 2-(2-Phenylethyl)chromone Derivatives

Abstract

Three new kinds of phenylethylchromone derivatives, called AH17, AH20 and AH23, were isolated from acetone and pyridine extracts of agalwood (Jinko) from Kalimantan. The structures of AH17 and AH23 were characterized as 5a,60,70-trihydroxy-8a-methoxy-2-(2-phenylethyl)-5,6,7,8-tetrahydrochromone and 5a,60,70,8a-tetrahydroxy-2-[2-(2-hydroxyphenyl)ethyl]5,6,7,8-tetrahydrochromone, respectively. AH20 was found to be a trimer formed by the ether-linkage made of 2-(2-phenylethyl)chromone and 2 mol of agarotetrol at C58, and C65,. © 1991, The Pharmaceutical Society of Japan. All rights reserved.