Lentiviral vectors enable gene transfer into target cells, but manufacturing is complex, scale-limited, and costly. Here, we describe the use of microfluidic devices for efficient ex vivo gene transfer. Up to four- to fivefold reductions in viral vector usage and two- to fourfold reductions in transduction times can be obtained by using this method.
CITATION STYLE
Tran, R., & Lam, W. A. (2020). Microfluidic approach for highly efficient viral transduction. In Methods in Molecular Biology (Vol. 2097, pp. 55–65). Humana Press Inc. https://doi.org/10.1007/978-1-0716-0203-4_3
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