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Journal ArticleOPEN ACCESS

Neutrophils and the S100A9 protein critically regulate granuloma formation

  • Yoshioka Y
  • Mizutani T
  • Mizuta S
  • et al.
Blood Advances (2016) 1(3) 184-192
DOI: 10.1182/bloodadvances.2016000497
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Abstract

S100A9+ neutrophils accumulated prominently in the central area of granulomas in humans and guinea pigs. Granuloma formation was markedly impaired by a treatment with the S100A9 inhibitor, tasquinimod.

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Yoshioka, Y., Mizutani, T., Mizuta, S., Miyamoto, A., Murata, S., Ano, T., … Sugita, M. (2016). Neutrophils and the S100A9 protein critically regulate granuloma formation. Blood Advances, 1(3), 184–192. https://doi.org/10.1182/bloodadvances.2016000497

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