Internal medical emergencies in the pregnant patient: Peripartum sepsis, metabolic derailment, endocrinological emergencies and pulmonary edema

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Abstract

Peripartum emergencies that require intensive medical care represent a major challenge for the interdisciplinary treatment team. Due to physiological changes in pregnant women symptoms can be masked and the initiation of treatment is delayed. Peripartum sepsis has a relatively high incidence. The anti-infective treatment depends on the spectrum of pathogens to be expected. Endocrinological emergencies are rare but can be fulminant and fatal. The development of ketoacidosis is favored by decreased bicarbonate buffer and placental hormones. In the case of thyrotoxicosis, propylthiouracil and thiamazole are available for treatment depending on the stage of gestation. Sheehan’s syndrome is an infarction of the anterior lobe of the pituitary gland during a hemorrhage. Due to the loss of production of vital hormones, this can be fatal. The development of pulmonary edema is just as acute. This is favored by physiological changes during pregnancy. The differentiation between hypertensive and hypotensive pulmonary edema is important for the causal treatment.

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Fischer, J., Gerresheim, G., & Schwemmer, U. (2021). Internal medical emergencies in the pregnant patient: Peripartum sepsis, metabolic derailment, endocrinological emergencies and pulmonary edema. Anaesthesist, 70(9), 795–808. https://doi.org/10.1007/s00101-021-00944-5

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