Cembranoid diterpenes from the soft corals Sarcophyton sp. and Sarcophyton glaucum

Abstract

Two new cembrane diterpenes, 17-hydroxysarcophytoxide (1) and 7β-acetoxy-8α-hydroxydeepoxysarcophine (2), together with 7β,8α-dihydroxydeepoxysarcophine (3), sarcophytonin A (4) and (-)-β-elemene (5) have been isolated from the soft coral Sarcophyton sp. 7β-Hydroxy-8α-methoxydeepoxysarcophytoxide (6) and 7α,8β-dihydroxydeepoxysarcophytoxide (7) have been obtained from the soft coral Sarcophyton glaucum. The structures were determined primarily by NMR spectroscopy.