Targeting a hydrophobic patch on the surface of the Grb2-SH2 domain leads to high-affinity phosphotyrosine-containing peptide ligands

  • Fretz H
  • Furet P
  • Schoepfer J
  • et al.
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Abstract

A symposium with two refs. A discussion of the design and complexation of a series of pTyr-contg. peptides with the SH2-domain of growth factor receptor binding protein 2 (Grb2) was given. [on SciFinder(R)]

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Fretz, H., Furet, P., Schoepfer, J., Garcia-Echeverria, C., Gay, B., Rahuel, J., & Caravatti, G. (2005). Targeting a hydrophobic patch on the surface of the Grb2-SH2 domain leads to high-affinity phosphotyrosine-containing peptide ligands. In Peptides Frontiers of Peptide Science (pp. 707–708). Kluwer Academic Publishers. https://doi.org/10.1007/0-306-46862-x_309

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