Efficient selective screening of haplotype tag SNPs

174Citations
Citations of this article
62Readers
Mendeley users who have this article in their library.

Abstract

Haplotypes defined by common single nucleotide polymorphisms (SNPs) have important implications for mapping of disease genes and human traits. Often only a small subset of the SNPs is sufficient to capture the full haplotype information. Such subsets of markers are called haplotype tagging SNPs (htSNPs). Although htSNPs can be identified by eye, efficient computer algorithms and flexible interactive software tools are required for large datasets such as the human genome haplotype map. We describe a java-based program, SNPtagger, which screens for minimal sets of SNP markers to represent given haplotypes according to various user requirements. The program offers several options for inclusion/exclusion of specific markers and presents alternative panels for final selection.

Cite

CITATION STYLE

APA

Ke, X., & Cardon, L. R. (2003). Efficient selective screening of haplotype tag SNPs. Bioinformatics, 19(2), 287–288. https://doi.org/10.1093/bioinformatics/19.2.287

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free