Measurement of the insulin delivery rate in man

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Abstract

A method for the quantitative assessment of rapid changes in the delivery rate of hormones into the systemic circulation is reported. Plasma hormone levels are examined in relation to the "non-steady-state" disappearance rate measured following an intravenous infusion of the hormone. The insulin delivery rate in response to iv glucose has been measured; a biphasic insulin response has been confirmed; and the amount of insulin entering the systemic circulation in each phase can be examined. © 1971 by The Endocrine Society.

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Turner, R. C., Grayburn, J. A., Newman, G. B., & Nabarro, J. D. N. (1971). Measurement of the insulin delivery rate in man. Journal of Clinical Endocrinology and Metabolism, 33(2), 279–286. https://doi.org/10.1210/jcem-33-2-279

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