O'Neill et al. use optogenetic control of two distinct migration modes to address the question of how propelling forces are generated during adhesion-independent cell migration. They show that rearward plasma membrane flow generates tangential viscous forces at the cell-liquid interface to drive the cell forward.
CITATION STYLE
O’Neill, P. R., Castillo-Badillo, J. A., Meshik, X., Kalyanaraman, V., Melgarejo, K., & Gautam, N. (2018). Membrane Flow Drives an Adhesion-Independent Amoeboid Cell Migration Mode. Developmental Cell, 46(1), 9-22.e4. https://doi.org/10.1016/j.devcel.2018.05.029
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