We present continuous-time models for age-structured populations and disease transmission. We show how to use the method of characteristic lines to analyze the model dynamics and to write an age-structured population model as an integral equation model. We then extend to an agestructured SIR epidemic model. As an example we describe an age-structured model for AIDS, derive a formula for the reproductive number of infection, and show how important a role pair-formation plays in the modeling process. In particular, we outline the semi-group method used in an age-structured AIDS model with non-random mixing. We also discuss models for populations and disease spread with discrete age structure. © 2008 Springer-Verlag Berlin Heidelberg.
CITATION STYLE
Li, J., & Brauer, F. (2008). Continuous-time age-structured models in population dynamics and epidemiology. Lecture Notes in Mathematics, 1945, 205–227. https://doi.org/10.1007/978-3-540-78911-6_9
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