Using animal models is considered a major method for studying osteoporosis in humans. Limitations in studying on human osteopenic patients, especially regarding new therapeutic methods, leave animal models as the only applicable choice.
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Hayashi, K., & Fotovati, A. (2002). Animal models of osteoporosis. In Orthopaedic Issues in Osteoporosis (pp. 71–89). CRC Press. https://doi.org/10.12681/jhvms.14936