Rheumatoid arthritis is progressive systemic disorder with poor outcomes. Better recognizing of the disease patophysiology resulted in changing therapeutic approaches in DMARDs treatment and creating new drugs. Combined therapy is accepted worldwide in the last 10 years. The rationale for combined treatment is that different drugs with different mechanisms of action can affect different disease pathways to achieve better outcomes.
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CITATION STYLE
Babić-Naglić, D. (1999). Combination therapy in rheumatoid arthritis. Reumatizam, 46(2), 7–11. https://doi.org/10.2492/jsir1981.12.413