Abstract
We describe the first catalytic generation of Fischer-type acyloxy Rh(II)-carbenes from carboxylic acids and Rh(II)-carbynoids. This novel class of transient donor/acceptor Rh(II)-carbenes evolved through a cyclopropanation process providing access to densely functionalized cyclopropyl-fused lactones with excellent diastereoselectivity. DFT calculations allowed the analysis of the properties of Rh(II)-carbynoids and acyloxy Rh(II)-carbenes as well as the characterization of the mechanism.
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CITATION STYLE
Palomo, E., Sharma, A. K., Wang, Z., Jiang, L., Maseras, F., & Suero, M. G. (2023). Generating Fischer-Type Rh-Carbenes with Rh-Carbynoids. Journal of the American Chemical Society, 145(9), 4975–4981. https://doi.org/10.1021/jacs.3c00012
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