Principles and Topical Applications of 19F NMR Spectrometry

Abstract

A review. F occurs naturally in only a few org. compds. In the chem. industry F is a substituent of choice used to modify synthetic substrates in expectation of conferring beneficial phys. properties. When incorporated, the spectroscopic properties of F make it a useful tool to aid the structural elucidation of the derived substances. F is generally resistant to degrdn. and offers interesting possibilities as a probe for the detn. of chem. residues and the investigation of metabolic processes. This chapter offers an overview of the ways in which the many recent advances in NMR technol. can be exploited to derive useful qual. and quant. chem. information from fluorinated substances. on SciFinder (R)