Bounce back: Ondansetron, CYP2D6 ultra-rapid metabolism

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Abstract

This case discusses a drug-gene interaction involving ondansetron. Ondansetron is a cytochrome P450 2D6 substrate. The patient depicted in this clinical scenario is a 2D6 ultrarapid metabolizer.

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Wittwer, E. D., Nicholson, W. T., & Sprung, J. (2015). Bounce back: Ondansetron, CYP2D6 ultra-rapid metabolism. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 725–728). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_162

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