Background: Glanders is a transmissible zoonotic disease caused by Burkholderia mallei that infects equids and humans. No glanders cases in equids were reported so far in Nepal. Case presentation: Following suspected glanders in animals with clinical signs in different regions in Nepal, serum samples were tested by CFT, ELISA and Luminex® tests. Two horses and a mule tested positive for glanders by all tests, while two other equids only tested positive by ELISA and Luminex®. Analysis of swabs and pus samples by a PCR system targeting B. mallei confirmed the presence of the bacterium in the samples collected from the 3 equids that yielded positive results in all serological tests. Genotyping of the three PCR positive samples with a SNP-based method identified a genotype closely related to the B. mallei strains circulating in India. Conclusion: Confirmation of glanders cases underscores the need of implementing a surveillance program in Nepal and a strict control of the animal movement across the borders.
CITATION STYLE
Koirala, P., Maharjan, M., Manandhar, S., Pandey, K. R., Deshayes, T., Wang, G., … Laroucau, K. (2022). First glanders cases detected in Nepal underscore the need for surveillance and border controls. BMC Veterinary Research, 18(1). https://doi.org/10.1186/s12917-022-03233-4
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