Fluid–Structure Interaction Modelling of Physiological Loading-Induced Canalicular Fluid Motion in Osteocyte Network

Abstract

The present study develops a fluid–structure Interaction (FSI) model to characterize the physiological loading-induced canalicular fluid motion in an osteocyte network within the bone. The effect of poromechanical properties on the canalicular fluid motion is also studied. The outcomes indicate that fluid motion in the network varies with gait events and fluid motion occurs from compressive to tensile strain environment. This work will provide a better understanding of osteocyte mechanical environment and biochemical communication regulating the bone’s adaptation which is although tedious to be explored using experimental techniques.