Percutaneous transluminal angioplasty for peripheral artery disease confers cardiorenal protection

6Citations
Citations of this article
19Readers
Mendeley users who have this article in their library.
Get full text

Abstract

The effects of percutaneous transluminal angioplasty (PTA) on hemodynamic parameters are not established. We tested the hypothesis that PTA would achieve reductions in hemodynamic and target organ damage (TOD) measures in patients with peripheral artery disease (PAD). We enrolled 56 consecutive PAD patients who were scheduled to undergo elective PTA procedures. Brachial blood pressure (BP), central BP, left ventricular mass index (LVMI) and urinary microalbumin excretion ratio (UACR) were assessed at baseline and follow-up. The ankle-brachial index in the diseased leg significantly improved after the PTA (P<0.001). Compared with the pretreatment levels, brachial and central BPs, the carotid augmentation index (AI) and central augmentation pressure (AP) were significantly reduced after the PTA, as were LVMI and UACR. The change in AI in the PTA group was significantly associated with the extent of change in LVMI (P=0.002) and marginally associated with the change in UACR (P=0.07), independently of other covariates. In conclusion, in patients with PAD, significant reductions in carotid AI were observed by PTA treatment; these changes may be attributable to improvements in measures of cardiac and renal target organ damage. © 2014 Macmillan Publishers Limited. © 2014 Macmillan Publishers Limited.

Cite

CITATION STYLE

APA

Eguchi, K., Murakami, A., Horaguchi, T., Kato, M., Miyashita, H., & Kario, K. (2014). Percutaneous transluminal angioplasty for peripheral artery disease confers cardiorenal protection. Journal of Human Hypertension, 28(1), 51–55. https://doi.org/10.1038/jhh.2013.37

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free