Switch from cytology-based to human papillomavirus test-based cervical screening: Implications for colposcopy

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Abstract

Human papillomavirus (HPV) testing is more sensitive than cytology; some cervical cancer prevention programs will switch from cytology to carcinogenic HPV test-based screening. The objective of our study is to evaluate the clinical implications of a switch to HPV test-based screening on performance and workload of colposcopy. Women in the population-based, 7-year Guanacaste cohort study were screened at enrollment using cytology. We also took another specimen for HPV DNA testing and collected magnified cervical photographic images (cervigrams). A final case diagnosis (≤yen;cervical intraepithelial neoplasia [CIN] grade 3, CIN2,

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Porras, C., Wentzensen, N., Rodríguez, A. C., Morales, J., Burk, R. D., Alfaro, M., … Schiffman, M. (2012). Switch from cytology-based to human papillomavirus test-based cervical screening: Implications for colposcopy. International Journal of Cancer, 130(8), 1879–1887. https://doi.org/10.1002/ijc.26194

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