Apparent diffusion coefficients (ADCs) of tissue water were determined in chronic brain lesions of a rat stroke model, the stroke-prone spontaneously hypertensive rat, and compared with histology. ADCs increased in the order normal < edema < gliosis < cyst. The differences between individual groups were statistically significant. The increase in ADC is thought to mainly reflect a relative increase in the extracellular space in brain tissue. ADC may be a new parameter for tissue characterization.
CITATION STYLE
Takahashi, M., Fritz-Zieroth, B., Chikugo, T., & Ogawa, H. (1994). In vivo differentiation of edematous changes after stroke in spontaneously hypertensive rats using diffusion weighted MRI. Acta Neurochirurgica. Supplementum, 60, 224–227. https://doi.org/10.1007/978-3-7091-9334-1_60
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