Abstract
We studied the presence of primary resistance to raltegravir (RAL), natural polymorphisms, and selection pressure on HIV-1 integrase. We found a high frequency of integrase polymorphisms related to the resistance to RAL and sequence stability. Further studies are needed to determine the importance of these polymorphisms to RAL resistance. Copyright © 2012, American Society for Microbiology. All Rights Reserved.
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CITATION STYLE
Mantovani, N. P., Azevedo, R. G., Rabelato, J. T., Sanabani, S., Diaz, R. S., & Komninakis, S. V. (2012). Analysis of transmitted resistance to raltegravir and selective pressure among HIV-1-infected patients on a failing HAART in São Paulo, Brazil. Journal of Clinical Microbiology, 50(6), 2122–2125. https://doi.org/10.1128/JCM.00539-12
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