Introduction: The emergence of multi-resistant enterobacteria and extended spectrum betalactamase producers in external consultation patients with urinary tract infections represents a public health problem in Peru. Objectives. Molecularly characterize multi-resistant enterobacteria isolated from patients diagnosed with urinary tract infection from two departments of the Peruvian jungle. Materials and methods. A descriptive, observational and retrospective study o 61 uroculture isolates from the Peruvian jungle was conducted during 2017 -2018. Resistance profiles were identified using the MicroScan automated system®. A conventional polymerase chain reaction was used for the detection of the genes blacTx-M, blaTEM, blasHv. Results. The most common positive ESBL enterobacteria for each department were Escherichia coli, Madre de Dios 25% (10/40) and Ucayali 76.2% (16/21). For both departments the gene blacrx-M was the most prevalent with 41 % (25/61), followed by blaTEM with 24.6% (15/61) and blasHv with 16.4% (10/61). Antimicrobial susceptibility profile detected resistance levels with 72.6% for ampicillin, 82.3% cephalotin and 88.7% for nitrofurantoin. Conclusions. BLEE-producing multi-resistant enterobacteria strains in both departments were 57.4%; with the blacrx-M gene being the most common.
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León-Luna, D., Fajardo-Loyola, A., Yareta-Yareta, J., Burgos-Espejo, A., Peralta-Siesquen, C., Galarza-Pérez, M., & Marcos-Carbajal, P. (2021). Molecular characterization of multi-resistant enterobacteria in two departments of the Peruvian jungle. Biomedica, 41, 1–22. https://doi.org/10.7705/biomedica.5720
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