Introduction. Well-documented cases of untreated cervical intra-epithelial dysplasia resulting in fatal progression of invasive cervical cancer are scarce because of a long pre-invasive state, the availability of cervical cytology screening programs, and the efficacy of the treatment of both pre-invasive and early-stage invasive lesions. Case presentation. We present a well-documented case of a 29-year-old Caucasian woman who was found, through routine conventional cervical cytology screening, to have pathologic Papanicolaou (Pap) grade III D lesions (squamous cell abnormalities). She subsequently died as a result of human papillomavirus type 18-associated cervical cancer after she refused all recommended curative therapeutic procedures over a period of 13 years. Conclusion: This case clearly demonstrates a caveat against the promotion and use of complementary alternative medicine as pseudo-immunologic approaches outside evidence-based medicine paths. It also demonstrates the impact of the individualized demands in diagnosis, treatment and palliative care of patients with advanced cancer express their will to refuse evidence-based treatment recommendations. © 2011 Braun et al; licensee BioMed Central Ltd.
CITATION STYLE
Braun, S., Reimer, D., Strobl, I., Wieland, U., Wiesbauer, P., Müller-Holzner, E., … Zeimet, A. G. (2011). Fatal invasive cervical cancer secondary to untreated cervical dysplasia: A case report. Journal of Medical Case Reports, 5. https://doi.org/10.1186/1752-1947-5-316
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