Abstract
HSP27 and MKBP translocate from the cytosolic to myofibril fraction in ischemic rat heart as demonstrated by immunoblotting. Immunohistochemistry analysis showed that ischemia enhances the Z line labeling of HSP27 and MKBP. Two dimensional gel eIectrophoresis showed that ischemia increases the hyperphosphorylated form of HSP27. These data suggest that HSP27 and MKBP may be involved in the Z line protection against postischemic reperfusion injury.
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Yoshida, K. I., Aki, T., Harada, K., Shama, K. M. A., Kamoda, Y., Suzuki, A., & Ohno, S. (1999). Translocation of HSP27 and MKBP in ischemic heart. Cell Structure and Function, 24(4), 181–185. https://doi.org/10.1247/csf.24.181
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