A MeOH extract from the whole plant Dendrobium venustum exhibited significant antimalarial and anti-herpetic activities. Bioassay-guided isolation of the plant extract resulted in the isolation of seven known phenolic compounds. Densiflorol B (3) and phoyunnanin E (6) showed the strongest antimalarial activity and a high selectivity index, whereas gigantol (2), batatasin III (5) and phoyunnanin C (7) exhibited moderate activity. Compounds 2 and 5 also showed weak activity against the Herpes simplex virus. This study is the first report on the chemical and biological activities of D. venustum.
CITATION STYLE
Sukphan, P., Sritularak, B., Mekboonsonglarp, W., Lipipun, V., & Likhitwitayawuid, K. (2014). Chemical constituents of Dendrobium venustum and their antimalarial and anti-herpetic properties. Natural Product Communications, 9(6), 825–827. https://doi.org/10.1177/1934578x1400900625
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