Bisheterocycles: Synthesis of some novel 1,2,3-triazolyl oxadiazole and 4(3H)-quinazolinones via azide cycloaddition reaction

Abstract

2,5-Bis[2-(4,5-dimethoxycarbonyl)1,2,3-triazol-1-yl)acetylaminophenyl]-1,3, 4-oxadiazole (4) and dimethyl 1-(2-{[(3-methyl-4-oxo-3,4-dihydro-2-quinazolinyl) methyl]anilino}-2-oxoethyl)-1H-1,2,3-triazole-4,5-dicarboxylate (6) are prepared by cycloaddition of dimethyl acetylenedicarboxylate to the oxadiazolyl azide 3 and the quinazolinone azide 5, respectively. ©ARKAT USA, Inc.