Development of PEGylated mammalian urate oxidase as a therapy for patients with refractory gout

  • Hershfield M
  • Sundy J
  • Ganson N
  • et al.
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Abstract

Gout is a form of arthritis caused by inflammatory crystals of monosodium urate, which deposit in joints when the plasma concentration of uric acid chronically exceeds the limit of solubility, ~7 mg/dL (0.

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Hershfield, M. S., Sundy, J. S., Ganson, N. J., & Kelly, S. J. (2009). Development of PEGylated mammalian urate oxidase as a therapy for patients with refractory gout. In PEGylated Protein Drugs: Basic Science and Clinical Applications (pp. 217–227). Birkhäuser Basel. https://doi.org/10.1007/978-3-7643-8679-5_13

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