Chiral amides in asymmetric synthesis

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Abstract

New strategies for the asymmetric vicinal acylation of olefins and the synthesis of enantiomerically pure amino acids are presented. Both use, as key step, a cycloaddition reaction involving a reagent easily prepared from chiral amides derived from pyrrolidines with C2 symmetry. © 1992, Walter de Gruyter. All rights reserved.

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Ghosez, L., Genicot, C., & Gouverneur, V. (1992). Chiral amides in asymmetric synthesis. Pure and Applied Chemistry, 64(12), 1849–1856. https://doi.org/10.1351/pac199264121849

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