PD-030 Prospective non-interventional study to collect data on the use of bevacizumab and conventional chemotherapy for the treatment of previously untreated metastatic colorectal cancer in patient's ≥70 years

Abstract

Methods: National, multicentre, prospective, non-interventional, post-authorization study. Patients ≥ 70 years with previous untreated mCRC and considered suitable to receive chemotherapy with or without bevacizumab were eligible for inclusion. Dosing and treatment were at the discretion of the investigator and in accordance with labelling. Primary objective was to observe in clinical practice the treatment duration in elderly patients with bevacizumab containing first-line chemotherapy for mCRC. Treatment duration with first line conventional chemotherapy, safety of bevacizumab in elderly, PFS and correlation with CGA scores were secondary objectives. In this observational study PFS assessments were not carried out at protocol pre-specified fixed intervals and were not independently assessed.