Empty follicle syndrome

Abstract

It is possible that the result of stimulation does not end in oocyte retrieval. One of the causes of non-retrieval of oocytes after an apparent normal stimulation cycle is Empty Follicle Syndrome (EFS). It is diagnosed after ruling out the other possible causes that could lead to non-retrieval of oocytes. EFS can be classified as genuine (GEFS) and false (FEFS). It is a highly stressful situation for both the couple undergoing the treatment and the clinical team. Hence, it is necessary to take steps to prevent it and apply a step-by-step formula to minimize it or its occurrence. EFS is a definite entity, and the clinicians would definitely see the cases of the same in the clinical practice.