Chinese herbal medicine for ulcerative colitis: A systematic review protocol

Abstract

Introductioo: This manuscript aims to provide a protocol of systematic review to assess the safety and effectiveness of Chinese herbal medicine (CHM) for the treatment of ulcerative colitis (UC). Although CHM has been widely used for UC, its effectiveness and safety has not yet been well defined and analyzed. Methods and analysis: Seven electronic databases were searched, including China National Knowledge Infrastructure (CNKI), Chinese Biomedical literature (CBL), VIP database, Cochrane Library, MEDLINE, PubMed and China Journals Full-text Database. Related Chinese literature will be searched in other Chinese databases. All relevant randomized controlled literature of publication type will be included. Assessment of risk of bias, data synthesis and subgroup analysis will be carried out using Review Manager 5.2. Ethics and dissemination: The results of the systematic review will be disseminated via publication in a peer-reviewed journal and presented at a relevant conference. Trail registartion number: PROSPERO CRD42015019350.