Aqueous exposures to selenomethionine (SeMet), the major form of selenium (Se) in the diet, represent a rapid and simplified method for determining the embryotoxic effects of SeMet. Using fathead minnows (Pimephales promelas) as a model test organism, the objective of this study was to evaluate the effects of waterborne exposure to elevated SeMet on embryos from fertilization to swim-up. Newly fertilized embryos were exposed for 6 days to 30, 90, 270, 810, 2430, 7290, 21,870, and 65,610 µg Se/L (as SeMet). Survival, hatchability, days to hatch, and the frequency and severity of deformities (total and type) were quantified. SeMet exposure reduced hatchability and days to hatch at concentrations ≥ 21870 µg/L. Significant decreases in survival and significant increases in the incidence and severity of deformities were observed at concentrations ≥ 810 µg/L. The results suggest that early life-stage fathead minnows are more tolerant to aqueous exposure to SeMet compared to medaka and zebrafish.
CITATION STYLE
Gerhart, A. K., Hecker, M., & Janz, D. M. (2019). Toxicity of Aqueous l-Selenomethionine Exposure to Early Life-Stages of the Fathead Minnow (Pimephales promelas). Bulletin of Environmental Contamination and Toxicology, 102(3), 323–328. https://doi.org/10.1007/s00128-018-02537-2
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