Sympathetic innervation in skeletal muscle and its role at the neuromuscular junction

7Citations
Citations of this article
18Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Neuromuscular junctions are the synapses between motor neurons and skeletal muscle fibers, which mediate voluntary muscle movement. Since neuromuscular junctions are also tightly associated with the capping function of terminal Schwann cells, these synapses have been classically regarded as tripartite chemical synapses. Although evidences from sympathetic innervation of neuromuscular junctions was described approximately a century ago, the essential presence and functional relevance of sympathetic contribution to the maintenance and modulation of neuromuscular junctions was demonstrated only recently. These findings shed light on the pathophysiology of different clinical conditions and can optimize surgical and clinical treatment modalities for skeletal muscle disorders.

Cite

CITATION STYLE

APA

Rudolf, R., Kettelhut, I. C., & Navegantes, L. C. C. (2024, June 1). Sympathetic innervation in skeletal muscle and its role at the neuromuscular junction. Journal of Muscle Research and Cell Motility. Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/s10974-024-09665-9

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free