Synovial fibroblast occur as two phenotypes - intimal and subintimal. The specialised intimal phenotype includes expression of uridine diphosphoglucose dehydrogenase (UDPGD), vascular cell adhesion molecule-1 (VCAM-1) and complement decay-accelerating factor (DAF). These gene products contribute to specialised functions relating to tissue movement and leucocyte traffic.
CITATION STYLE
Edwards, J. C. W. (2000). Fibroblast biology. Development and differentiation of synovial fibroblasts in arthritis. Arthritis Research. https://doi.org/10.1186/ar110
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