Allylation of functionalized aldehydes by potassium allyltrifluoroborate catalyzed by 18-Crown-6 in aqueous media

Abstract

An efficient method for the allylation of aldehydes containing a broad range of functional groups using potassium allyltrifluoroborate is described. The reaction utilizes a catalytic amount of 18-C-6 in biphasic media under open atmosphere and room temperature to provide the corresponding homoallylic alcohols in high yields and without the necessity of any subsequent purification. © 2012 by the authors.