Fixed-dose vs free-dose combinations for the management of hypertension—An analysis of 81 958 patients

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Abstract

Fixed-dose combinations (FDC) have been developed to reduce the pill burden for hypertensive patients. Data on fixed-dose or free-dose (freeDC) ramipril/amlodipine (R/A) or candesartan/amlodipine (C/A) combination treatment initiation were assessed. 71 463 patients were prescribed R/A and 10 495 C/A. For both R/A and C/A, FDC patients were younger (both P

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Bramlage, P., Schmidt, S., & Sims, H. (2018). Fixed-dose vs free-dose combinations for the management of hypertension—An analysis of 81 958 patients. Journal of Clinical Hypertension, 20(4), 705–715. https://doi.org/10.1111/jch.13240

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