Cost-effectiveness of a stepped care intervention to prevent depression and anxiety in late life: Randomised trial

Abstract

Background There is an urgent need for the development of costeffective preventive strategies to reduce the onset of mental disorders. Aims To establish the cost-effectiveness of a stepped care preventive intervention for depression and anxiety disorders in older people at high risk of these conditions, compared with routine primary care. Method An economic evaluation was conducted alongside a pragmatic randomised controlled trial (ISRCTN26474556). Consenting individuals presenting with subthreshold levels of depressive or anxiety symptoms were randomly assigned to a preventive stepped care programme (n=86) or to routine primary care (n = 84). Results The intervention was successful In halving the incidence rate of depression and anxiety at €563 (£412) per recipient and €4367 (£3196) per disorder-free year gained, compared with routine primary care. The latter would represent good value for money if the willingness to pay for a disorder-free year is at least €5000. conclusions The prevention programme generated depression- and anxiety-free survival years in the older population at affordable cost.