Neuropsychological sequelae of type 1 and type 2 diabetes

Abstract

Type 1 diabetes (T1D) or insulin-dependent diabetes is an endocrine disorder of insulin deficiency secondary to pancreatic β-cell destruction. Exogenous insulin replacement is imperfect and results in variable blood glucose levels with risk of glucose excess or hyperglycemia, and glucose insufficiency or hypoglycemia. The American Diabetes Association reports an incidence of 17.9 million cases of diabetes diagnosed among children and adults in the United States in 2007. An additional 5.7 million cases are undiagnosed [1]. Type 1 diabetes accounts for 5-10% of all diagnosed diabetes patients [2]. © 2010 Springer Science+Business Media, LLC.