One of the most satisfying aspects of a genome sequencing project is the identification of the genes contained within it.These are of two types: those which encode tRNAs and those which produce proteins. After a general introduction on the properties of protein-encoding genes and the utility of the Basic Local Alignment Search Tool (BLASTX) to identify genes through homologs, a variety of tools are discussed by their creators. These include for genome annotation: GeneMark, Artemis, and BASys; and, for genome comparisons: Artemis Comparison Tool (ACT), Mauve, CoreGenes, and GeneOrder.
CITATION STYLE
Kropinski, A. M., Borodovsky, M., Carver, T. J., Cerdeño-Tárraga, A. M., Darling, A., Lomsadze, A., … Wishart, D. S. (2009). In silico identification of genes in bacteriophage DNA. Methods in Molecular Biology (Clifton, N.J.), 502, 57–89. https://doi.org/10.1007/978-1-60327-565-1_6
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