Biomechanical properties of the cranial dura mater with puncture defects: An In Vitro study

Abstract

Objective: The primary aim of this investigation was to explore the nature of dura mater biomechanics following the introduction of puncture defect(s). Methods: Twenty-eight dura mater specimens were collected during autopsy from the department of forensic medicine of the authors’ institution. Specimens were divided randomly into one of four groups: group I (cranial dura mater; n=7), group II (cranial dura mater with one puncture defect; n=7); group III (cranial dura mater with two puncture defects; n=7), and group IV (cranial dura mater with three puncture defects; n=7). Results: The mean±standard deviation tensile strengths of the dura mater were 8.35±3.16, 8.22±3.32, 7.13±1.77, and 6.94±1.93 MPa for groups I, II, III, and IV, respectively. There was no statistical difference between all groups. A single, two or more punctures of the dura mater using a 20-gauge Quincke needle did not affect cranial dura tensile strength. Conclusion: This biomechanical study may contribute to the future development of artificial dura mater substitutes and medical needles that have a lower negative impact on the biomechanical properties of dura mater.