Production of Cellulase by Solid-State Fermentation

Abstract

The advances in the production of cellulase by solid-state fermentation are reviewed. In the process description of solid-state fermentation for cellulase production, the microorganisms, raw materials for solid-state fermentation, pretreatment of raw materials, sterilization and inoculation, and solid-state fermentation process are included. The effects and control of operating conditions, such as temperature,water content and water activity, pH, aeration, and substrate, are presented. A total of eight types of bioreactors with their advantages and disadvantages for solid-state fermentation are discussed. From the engineering aspect, mathematical models for the solid-state fermentation process are also discussed and several suggestions are proposed which might further research and development of cellulase production by the solid-state fermentation process.