Mitogen-activated protein kinase (MAPK) signaling influences a variety of cellular responses, ranging from stimulation of cell proliferation to induction of senescence and/or apoptosis. Ca(2+) is a ubiquitous intracellular signaling molecule that controls multiple processes in cells. Published evidence has identified both direct and indirect interactions between the Ca(2+) and MAPK signaling pathways. Here, we describe assays to accurately determine the effect of changes in intracellular Ca(2+) concentration on MAPK activation.
CITATION STYLE
White, C. D., & Sacks, D. B. (2010). Regulation of MAP kinase signaling by calcium. Methods in Molecular Biology (Clifton, N.J.), 661, 151–165. https://doi.org/10.1007/978-1-60761-795-2_9
Mendeley helps you to discover research relevant for your work.