Preliminary evaluation of the larvicidal activity of extracts and fractions from ocotea nutans (Nees) mez against aedes aegypti

Abstract

Introduction: Aedes aegypti is the main vector of dengue and yellow fever. Recently, the use of plant-sourced larvicides has gained momentum. Methods: The hydroethanolic extracts and fractions of Ocotea nutans leaves and stems were bioassayed to determine the larvicidal efficacy of these samples. Results: S-HEX (hexane fraction from the crude stem extract) demonstrated high potential for controlling third-stage larvae, with an LC50 of 14.14 µg.mL-1 (concentration required to inhibit 50% of the treated larvae). Conclusions: Extracts from O. nutans were effective against third-stage larvae of A. aegypti after 24 h of exposure.